DolphinNext: a distributed data processing platform for high throughput genomics.

ABSTRACT:

Background

The emergence of high throughput technologies that produce vast amounts of genomic data, such as next-generation sequencing (NGS) is transforming biological research. The dramatic increase in the volume of data, the variety and continuous change of data processing tools, algorithms and databases make analysis the main bottleneck for scientific discovery. The processing of high throughput datasets typically involves many different computational programs, each of which performs a specific step in a pipeline. Given the wide range of applications and organizational infrastructures, there is a great need for highly parallel, flexible, portable, and reproducible data processing frameworks. Several platforms currently exist for the design and execution of complex pipelines. Unf

SUBMITTER: Yukselen O 

PROVIDER: S-EPMC7168977 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature