Ontology highlight
ABSTRACT:
SUBMITTER: Virchow JC
PROVIDER: S-EPMC7168990 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20200419
<h4>Background</h4>A post hoc analysis of two randomized, placebo-controlled, Phase 3 trials of intravenous reslizumab, an anti-interleukin-5 (IL-5) biologic for severe eosinophilic asthma.<h4>Methods</h4>Relationships between baseline blood eosinophil levels (EOS), forced expiratory volume in 1 s (FEV<sub>1</sub>) reversibility to β<sub>2</sub>-agonists and treatment outcomes were assessed.<h4>Results</h4>Mean baseline FEV<sub>1</sub> reversibility was numerically lower among patients with high ...[more]