A novel 20-gene prognostic score in pancreatic adenocarcinoma.
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ABSTRACT:
SUBMITTER: Demirkol Canl? S
PROVIDER: S-EPMC7170253 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
A novel 20-gene prognostic score in pancreatic adenocarcinoma.
Demirkol Canlı Seçil S Dedeoğlu Ege E Akbar Muhammad Waqas MW Küçükkaraduman Barış B İşbilen Murat M Erdoğan Özge Şükrüoğlu ÖŞ Erciyas Seda Kılıç SK Yazıcı Hülya H Vural Burçak B Güre Ali Osmay AO
PloS one 20200420 4
Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal cancers. Known risk factors for this disease are currently insufficient in predicting mortality. In order to better prognosticate patients with PDAC, we identified 20 genes by utilizing publically available high-throughput transcriptomic data from GEO, TCGA and ICGC which are associated with overall survival and event-free survival. A score generated based on the expression matrix of these genes was validated in two independent coh ...[more]
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