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Functional connectivity of the right inferior frontal gyrus and orbitofrontal cortex in depression.

ABSTRACT: The orbitofrontal cortex extends into the laterally adjacent inferior frontal gyrus. We analyzed how voxel-level functional connectivity of the inferior frontal gyrus and orbitofrontal cortex is related to depression in 282 people with major depressive disorder (125 were unmedicated) and 254 controls, using FDR correction P?

SUBMITTER: Rolls ET 

PROVIDER: S-EPMC7171374 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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Functional connectivity of the right inferior frontal gyrus and orbitofrontal cortex in depression.

Rolls Edmund T ET   Cheng Wei W   Du Jingnan J   Wei Dongtao D   Qiu Jiang J   Dai Dan D   Zhou Qunjie Q   Xie Peng P   Feng Jianfeng J  

Social cognitive and affective neuroscience 20200101 1

The orbitofrontal cortex extends into the laterally adjacent inferior frontal gyrus. We analyzed how voxel-level functional connectivity of the inferior frontal gyrus and orbitofrontal cortex is related to depression in 282 people with major depressive disorder (125 were unmedicated) and 254 controls, using FDR correction P < 0.05 for pairs of voxels. In the unmedicated group, higher functional connectivity was found of the right inferior frontal gyrus with voxels in the lateral and medial orbit  ...[more]

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