Ontology highlight
ABSTRACT:
SUBMITTER: Selvaraj V
PROVIDER: S-EPMC7171652 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Selvaraj Vimal V Stocco Douglas M DM
Trends in endocrinology and metabolism: TEM 20150321 7
Translocator protein (TSPO), previously known as the peripheral benzodiazepine receptor (PBR), is an outer mitochondrial membrane protein. TSPO has been shown to cooperate with steroidogenic acute regulatory protein (StAR) and function in the transport of cholesterol into mitochondria. TSPO has also been considered as a structural component of the mitochondrial permeability transition pore (MPTP). However, recent advances have changed these views of TSPO's functions and have prompted a re-evalua ...[more]