Ontology highlight
ABSTRACT:
SUBMITTER: Lewandowska DW
PROVIDER: S-EPMC7172999 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Lewandowska Dagmara W DW Zagordi Osvaldo O Zbinden Andrea A Schuurmans Macé M MM Schreiber Peter P Geissberger Fabienne-Desirée FD Huder Jon B JB Böni Jürg J Benden Christian C Mueller Nicolas J NJ Trkola Alexandra A Huber Michael M
Diagnostic microbiology and infectious disease 20150629 2
Multiplex PCR assays for respiratory viruses are widely used in routine diagnostics, as they are highly sensitive, rapid, and cost effective. However, depending on the assay system, cross-reactivity between viruses that share a high sequence homology as well as detection of rare virus isolates with sequence variations can be problematic. Virus sequence-independent metagenomic high-throughput sequencing allows for accurate detection of all virus species in a given sample, as we demonstrate here f ...[more]