Genomic release-recapture experiment in the wild reveals within-generation polygenic selection in stickleback fish.

ABSTRACT: How rapidly natural selection sorts genome-wide standing genetic variation during adaptation remains largely unstudied experimentally. Here, we present a genomic release-recapture experiment using paired threespine stickleback fish populations adapted to selectively different lake and stream habitats. First, we use pooled whole-genome sequence data from the original populations to identify hundreds of candidate genome regions likely under divergent selection between these habitats. Next, we generate F2 hybrids from the same lake-stream population pair in the laboratory and release thousands of juveniles into a natural stream habitat. Comparing the individuals surviving one year of stream selection to a reference sample of F2 hybrids allows us to detect frequency shifts across the candidate

SUBMITTER: Laurentino TG 

PROVIDER: S-EPMC7174299 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature