Ontology highlight
ABSTRACT:
SUBMITTER: Bottomley AL
PROVIDER: S-EPMC7174318 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Bottomley Amy L AL Peterson Elizabeth E Iosifidis Gregory G Yong Adeline Mei Hui AMH Hartley-Tassell Lauren E LE Ansari Shirin S McKenzie Chris C Burke Catherine C Duggin Iain G IG Kline Kimberly A KA Harry Elizabeth J EJ
Scientific reports 20200421 1
Characterisation of protein function based solely on homology searches may overlook functions under specific environmental conditions, or the possibility of a protein having multiple roles. In this study we investigated the role of YtfB, a protein originally identified in a genome-wide screen to cause inhibition of cell division, and has demonstrated to localise to the Escherichia coli division site with some degree of glycan specificity. Interestingly, YtfB also shows homology to the virulence ...[more]