Ontology highlight
ABSTRACT:
SUBMITTER: Pinheiro DJLL
PROVIDER: S-EPMC7174408 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Pinheiro Daniel J L L DJLL Oliveira Leandro F LF Souza Isis N O INO Brogin João A Ferres JAF Bueno Douglas D DD Miranda Iranaia Assunção IA Da Poian Andrea T AT Ferreira Sergio T ST Figueiredo Claudia P CP Clarke Julia R JR Cavalheiro Esper A EA Faber Jean J
Scientific reports 20200421 1
Modulation of brain activity is one of the main mechanisms capable of demonstrating the synchronization dynamics of neural oscillations. In epilepsy, modulation is a key concept since seizures essentially result from neural hypersynchronization and hyperexcitability. In this study, we have introduced a time-dependent index based on the Kullback-Leibler divergence to quantify the effects of phase and frequency modulations of neural oscillations in neonatal mice exhibiting epileptiform activity in ...[more]