Disentangling the impact of environmental and phylogenetic constraints on prokaryotic within-species diversity.

ABSTRACT: Microbial organisms inhabit virtually all environments and encompass a vast biological diversity. The pangenome concept aims to facilitate an understanding of diversity within defined phylogenetic groups. Hence, pangenomes are increasingly used to characterize the strain diversity of prokaryotic species. To understand the interdependence of pangenome features (such as the number of core and accessory genes) and to study the impact of environmental and phylogenetic constraints on the evolution of conspecific strains, we computed pangenomes for 155 phylogenetically diverse species (from ten phyla) using 7,000 high-quality genomes to each of which the respective habitats were assigned. Species habitat ubiquity was associated with several pangenome features. In particular, core-genome size was

SUBMITTER: Maistrenko OM 

PROVIDER: S-EPMC7174425 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature