Adherence to the SEP-1 Sepsis Bundle in Hospital-Onset v. Community-Onset Sepsis: a Multicenter Retrospective Cohort Study.

ABSTRACT:

Background

Sepsis is the leading cause of in-hospital death. The SEP-1 sepsis bundle is a protocol for early sepsis care that requires providers to diagnose and treat sepsis quickly. Limited evidence suggests that adherence to the sepsis bundle is lower in cases of hospital-onset sepsis.

Objective

To compare sepsis bundle adherence in hospital-onset vs. community-onset sepsis.

Design

Retrospective cohort study using multivariable analysis of clinical data.

Participants

A total of 4658 inpatients age 18 or older were identified by diagnosis codes consistent with sepsis or disseminated infection.

Setting

Four university hospitals in California between 2014 and 2016.

Main outcomes and measures

The primary outcome was adherence to key components of th

SUBMITTER: Baghdadi JD 

PROVIDER: S-EPMC7174506 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature