Ontology highlight
ABSTRACT:
SUBMITTER: Hoter A
PROVIDER: S-EPMC7174549 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Hoter Abdullah A Rizk Sandra S Naim Hassan Y HY
Frontiers in molecular biosciences 20200415
Heat shock protein 60 (HSP60) is a mitochondrial chaperone that is implicated in physiological and pathological processes. For instance, it contributes to protein folding and stability, translocation of mitochondrial proteins, and apoptosis. Variations in the expression levels of HSP60 have been correlated to various diseases and cancers, including hepatocellular carcinoma (HCC). Unlike other HSPs which clearly increase in some cancers, data about HSP60 levels in HCC are controversial and diffic ...[more]