Ontology highlight
ABSTRACT:
SUBMITTER: Benn A
PROVIDER: S-EPMC7175193 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Benn Andreas A Alonso Florian F Mangelschots Jo J Génot Elisabeth E Lox Marleen M Zwijsen An A
Biomolecules 20200323 3
Vascular development is an orchestrated process of vessel formation from pre-existing vessels via sprouting and intussusceptive angiogenesis as well as vascular remodeling to generate the mature vasculature. Bone morphogenetic protein (BMP) signaling via intracellular SMAD1 and SMAD5 effectors regulates sprouting angiogenesis in the early mouse embryo, but its role in other processes of vascular development and in other vascular beds remains incompletely understood. Here, we investigate the func ...[more]