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Potential therapeutic agents against COVID-19: What we know so far.


ABSTRACT: The emerging outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 continues to spread all over the world. Agents or vaccines of proven efficacy to treat or prevent human coronavirus infection are in urgent need and are being investigated vigorously worldwide. This review summarizes the current evidence of potential therapeutic agents, such as lopinavir/ritonavir, remdesivir, favipiravir, chloroquine, hydroxychloroquine, interferon, ribavirin, tocilizumab, and sarilumab. More clinical trials are being conducted for further confirmation of the efficacy and safety of these agents in treating COVID-19.

SUBMITTER: Lu CC 

PROVIDER: S-EPMC7176266 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Potential therapeutic agents against COVID-19: What we know so far.

Lu Chih-Chia CC   Chen Mei-Yu MY   Lee Wan-Shin WS   Chang Yuh-Lih YL  

Journal of the Chinese Medical Association : JCMA 20200601 6


The emerging outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 continues to spread all over the world. Agents or vaccines of proven efficacy to treat or prevent human coronavirus infection are in urgent need and are being investigated vigorously worldwide. This review summarizes the current evidence of potential therapeutic agents, such as lopinavir/ritonavir, remdesivir, favipiravir, chloroquine, hydroxychloroquine, interferon, ribavir  ...[more]

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