Ontology highlight
ABSTRACT:
SUBMITTER: Lao MX
PROVIDER: S-EPMC7176443 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Chinese medical journal 20200401 8
Long non-coding RNA (lncRNA) plays a contributory role in rheumatoid arthritis (RA). In this review, we summarized the current findings of lncRNAs in RA, including cellular function and the potential mechanisms. Serum lncRNA levels are associated with serum proinflammatory cytokines and disease activity. LncRNAs regulate proliferation, migration, invasion and apoptosis of RA fibroblast-like synoviocytes (FLSs), modulate the differentiation of T lymphocytes and macrophages, and affect bone format ...[more]