Ontology highlight
ABSTRACT:
SUBMITTER: Rusnati M
PROVIDER: S-EPMC7177952 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20200331 7
Cystic fibrosis transmembrane conductance regulator (CFTR)-rescuing drugs have already transformed cystic fibrosis (CF) from a fatal disease to a treatable chronic condition. However, new-generation drugs able to bind CFTR with higher specificity/affinity and to exert stronger therapeutic benefits and fewer side effects are still awaited. Computational methods and biosensors have become indispensable tools in the process of drug discovery for many important human pathologies. Instead, they have ...[more]