Dataset Information

Effects of subgingival air-polishing with trehalose powder on oral biofilm during periodontal maintenance therapy: a randomized-controlled pilot study.

ABSTRACT:

Background

This pilot study was part of a larger study which compared the effect of subgingival air-polishing using trehalose powder with sonic scaling on clinical parameters during supportive periodontal therapy. Within this microbiological part of the investigation subgingival samples were taken from 10 participants to analyze the survival of different bacterial species after the two different treatments as a proof of principle.

Methods

In 10 participants two non-adjacent, single-root teeth requiring treatment (PD =5?mm with bleeding on probing (BOP) or?>?5?mm) were selected following a split-mouth design and were treated either with a sonic scaler or air-polishing device and trehalose powder. For persistent pockets (PD =4?mm and BOP or > 4?mm), treatment was repeated after 3?months. Subgingival biofilm samples were taken at baseline (BL), subsequently and three and six months after treatment. After determination of the bacterial counts (TBL), isolated bacteria were identified by MALDI-TOF-MS. If unsuccessful, PCR and 16S rDNA sequencing were performed.

Results

In both treatment groups, TBL decreased immediately after treatment remaining at a lower level. This confirms the findings of the larger study regarding clinical parameters showing a comparable effect on PD, BOP and CAL. Immediately after treatment, the diversity of detected species decreased significantly more than in the sonic group (p?=?0.03). After 3?months, the proportion of Gram-positive anaerobic rods was lower in the air-polishing group (powder/ sonic 7%/ 25.9%, p?=?0.025). Also, there was a greater reduction of Gram-negative aerobic rods for this group at this time (air-polishing/ sonic -?0.91 / -0.23 Log10 cfu/ ml, p?=?0.020).

Conclusion

Within the limitations of this study air-polishing and sonic treatment seem to have a comparable effect on the subgingival oral biofilm during supportive periodontal treatment.

Trial registration

The study was registered in an international trial register (German Clinical Trial Register number DRKS 00006296) on 10th of June 2015. HTML&TRIAL_ID?=?DRKS00006296.

SUBMITTER: Kruse AB

PROVIDER: S-EPMC7178568 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Publications

Effects of subgingival air-polishing with trehalose powder on oral biofilm during periodontal maintenance therapy: a randomized-controlled pilot study.

Kruse Anne B AB Maamar Rabie R Akakpo Dodji L DL Woelber Johan P JP Wittmer Annette A Vach Kirstin K Ratka-Krüger Petra P Al-Ahmad Ali A

BMC oral health 20200422 1

<h4>Background</h4>This pilot study was part of a larger study which compared the effect of subgingival air-polishing using trehalose powder with sonic scaling on clinical parameters during supportive periodontal therapy. Within this microbiological part of the investigation subgingival samples were taken from 10 participants to analyze the survival of different bacterial species after the two different treatments as a proof of principle.<h4>Methods</h4>In 10 participants two non-adjacent, singl ...[more]

PMID: 32321490

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Dataset Information

Effects of subgingival air-polishing with trehalose powder on oral biofilm during periodontal maintenance therapy: a randomized-controlled pilot study.

Background

Methods

Results

Conclusion

Trial registration

Publications

Effects of subgingival air-polishing with trehalose powder on oral biofilm during periodontal maintenance therapy: a randomized-controlled pilot study.

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