Dataset Information

OCT proves that vitreomacular adhesion is significantly more likely to develop vision-threatening retinal complications than vitreomacular separation.

ABSTRACT:

Background

SD-OCT is becoming commonplace in everyday practice. Vitreomacular adhesions (VMAs) are being more routinely diagnosed. Predictive studies to the natural course of VMA are thus clinically significant. Spectral domain-optical coherence tomography (SD-OCT) was presently utilized to analyze the incidence of floaters, the complete vitreomacular separation or VMA, the VMA complication, the vitreomacular angle (VMAng), and the complication mechanism.

Methods

Monthly SD-OCT was performed on patients with/without symptomatic floaters. OCT allowed VMA and vitreomacular separation to be compared. The incidence was assessed applying one-tailed Fisher's exact tests. The VMAngs between the inner retina and posterior hyaloid were measured, and the complication mechanism was studied using OCT image. For macular hole (MH), pre- and/or post-operative best corrected visual acuities (BCVAs; LogMAR), refractions and photoreceptor conditions were also evaluated.

Results

Totally, 124 eyes were included; there were 116 eyes with VMA and 8 eyes with vitreomacular separation. Considering the percentages over 124 eyes, floaters were present in 14.5% of enrolled eyes (=18/124), consisting of 12.9% of eyes with VMA (16/124) and 1.6% of eyes with vitreomacular separation (2/124). Moreover, there were twelve eyes (9.7%) with VMA-associated vision-threatening complications, including MH (n?=?8; 6.5%), retinal detachment (RD; n?=?2; 1.6%), vitreomacular traction (VMT; n?=?1; 0.8%) and macular pucker (MP; n?=?1; 0.8%). Eyes with initial VMA had a significantly greater possibility of complications than eyes with initial vitreomacular separation (p?=?0.03). Among these eyes with MH (n?=?8), the pre-operative BCVA (LogMAR) was 1.1?±?0.5, which was insignificantly (p?=?0.35) improved to 0.8?±?0.7 post-operatively. The VMAng of VMA eyes with MHs was 24.2?±?24.9° (n?=?8). The critical VMAng was 13.3°.

Conclusions

A minority of eyes with VMA or vitreomacular separation had floaters. Moreover, the use of SD-OCT could identify vision-threatening sequelae, namely MH, RD, MP and VMT, and this was significantly more frequent in eyes with VMA than in eyes with complete vitreomacular separation. Therefore, SD-OCT might be a useful way of identifying either identity, and evaluating VMA-associated complications. Whether VMA eyes with MH (n?=?8) that have a VMAng greater than critical VMAng have a greater likelihood of tangential traction and subsequent MH needs further investigation.

SUBMITTER: Liao DY

PROVIDER: S-EPMC7178608 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Publications

OCT proves that vitreomacular adhesion is significantly more likely to develop vision-threatening retinal complications than vitreomacular separation.

Liao Ding-Ying DY Liu Jorn-Hon JH Zheng Yu-Ping YP Shiu Huei-Wen HW Wang Jian-Ming JM Chao Hsiao-Ming HM

BMC ophthalmology 20200422 1

<h4>Background</h4>SD-OCT is becoming commonplace in everyday practice. Vitreomacular adhesions (VMAs) are being more routinely diagnosed. Predictive studies to the natural course of VMA are thus clinically significant. Spectral domain-optical coherence tomography (SD-OCT) was presently utilized to analyze the incidence of floaters, the complete vitreomacular separation or VMA, the VMA complication, the vitreomacular angle (VMAng), and the complication mechanism.<h4>Methods</h4>Monthly SD-OCT wa ...[more]

PMID: 32321473

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Dataset Information

OCT proves that vitreomacular adhesion is significantly more likely to develop vision-threatening retinal complications than vitreomacular separation.

Background

Methods

Results

Conclusions

Publications

OCT proves that vitreomacular adhesion is significantly more likely to develop vision-threatening retinal complications than vitreomacular separation.

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