Dataset Information

Analytic Hierarchy Process-Based Construction Material Selection for Performance Improvement of Building Construction: The Case of a Concrete System Form.

ABSTRACT: Selecting the best materials that ensure maximum performance is crucial in the construction engineering design of any construction project. However, this is challenging and usually not properly considered because of the lack of systematic and scientific evaluation methods for the performance of materials. This paper proposes a new approach of selecting material to satisfy the performance goal of material designers in building constructions based on the analytic hierarchy process method. To validate the suggested model, a case study was conducted for a concrete system form, the performance of which is susceptible to its materials and has a strong effect on overall project productivity. The newly developed form comprising polymers and alloys showed that the proposed material selection model provided a better combination of materials, and the solution was technically more advanced and ensured better performance. This paper contributes to the body of knowledge by expanding the understanding of how construction material properties affect project performance and provides a guideline for material engineers to select the best-performing building materials while considering a performance goal.

SUBMITTER: Lee D

PROVIDER: S-EPMC7178692 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Analytic Hierarchy Process-Based Construction Material Selection for Performance Improvement of Building Construction: The Case of a Concrete System Form.

Lee Dongmin D Lee Dongyoun D Lee Myungdo M Kim Minju M Kim Taehoon T

Materials (Basel, Switzerland) 20200408 7

Selecting the best materials that ensure maximum performance is crucial in the construction engineering design of any construction project. However, this is challenging and usually not properly considered because of the lack of systematic and scientific evaluation methods for the performance of materials. This paper proposes a new approach of selecting material to satisfy the performance goal of material designers in building constructions based on the analytic hierarchy process method. To valid ...[more]

PMID: 32276420

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Project description:Fecal microbiota transplantation (FMT) targeting gut microbiota has recently been applied to the treatment of ulcerative colitis (UC). However, preliminary trials showed that only a subset of patients responded to FMT, and the heterogeneity in donor gut microbiota probably played important roles in patients' responses, implying the significance of matching an appropriate donor to a specified patient. We developed a strategy to build a donor-recipient matching model to guide rational donor selection for UC in FMT. We collected and uniformly reanalyzed 656 fecal 16S rRNA gene sequencing samples (350 from UC patients and 306 from healthy subjects) from 9 studies. Significantly lower α-diversity indexes were observed in UC patients by random effects model. Thirty-four bacterial genera and 34 predicted pathways were identified with significant odds ratios and classification potentials for UC patients. Based on six bacterial indicators, including richness, overall distance, genera, and pathways (beneficial and harmful), the analytic hierarchy process-based donor-recipient matching model was set to rank and select appropriate donors for patients with UC. Finally, the model showed favorable classification powers (>70%) for FMT effectiveness in two previous clinical trials. This study revealed the dysbiosis of fecal bacterial diversity, composition, and predicted pathways of patients with UC by meta-analysis and hereby developed a donor-recipient matching strategy to guide donor selection for UC in FMT. This strategy can also be applied to other diseases associated with gut microbiota. IMPORTANCE Modulation of gut microbiota by FMT from donors has been applied to the treatment of UC and yielded variable effectiveness in clinical trials. One possibility is that this variable effectiveness was related to donor selection, as a patient's response to FMT may rely on the capability of the used donor's microbiota to restore the specific gut disturbances of the patient. However, the biggest issues on the practical level are what should be considered in the selection process and how to set up such a donor-recipient matching model. In this study, we presented a bacterial profile-based donor-recipient matching strategy to guide donor selection for UC in FMT by first meta-analysis of 656 fecal 16S rRNA gene sequencing samples from 9 studies to identify significant indicators and then setting up the model by an analytic hierarchy process. The applicability and accuracy of this model were verified in the data sets from two previous FMT clinical studies. Our data indicate that the donor-recipient matching model built in this study enables researchers to rationally select donors for UC patients in FMT clinical practice, although it needs more samples and prospective trials for validation. The strategy adopted in this study to leverage existing data sets to build donor-recipient matching models for precision FMT is feasible for other diseases associated with gut microbiota.

Dataset Information

Analytic Hierarchy Process-Based Construction Material Selection for Performance Improvement of Building Construction: The Case of a Concrete System Form.

Publications

Analytic Hierarchy Process-Based Construction Material Selection for Performance Improvement of Building Construction: The Case of a Concrete System Form.

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