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First Occurrence of the OXA-198 Carbapenemase in Enterobacterales.


ABSTRACT: A carbapenem-resistant Citrobacter sp. was recovered from routine screening of multidrug-resistant bacteria. This isolate coproduced OXA-48 and OXA-198. OXA-48 was carried by the prototypical IncL plasmid, whereas OXA-198 was carried by a peculiar IncHI-type plasmid. This carbapenemase gene was inserted within a class 1 integron located on a conjugative plasmid. This report describes the first occurrence of OXA-198 in Enterobacterales.

SUBMITTER: Bonnin RA 

PROVIDER: S-EPMC7179269 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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First Occurrence of the OXA-198 Carbapenemase in <i>Enterobacterales</i>.

Bonnin Rémy A RA   Jousset Agnès B AB   Gauthier Lauraine L   Emeraud Cécile C   Girlich Delphine D   Sauvadet Aimie A   Cotellon Garance G   Jové Thomas T   Dortet Laurent L   Naas Thierry T  

Antimicrobial agents and chemotherapy 20200324 4


A carbapenem-resistant <i>Citrobacter</i> sp. was recovered from routine screening of multidrug-resistant bacteria. This isolate coproduced OXA-48 and OXA-198. OXA-48 was carried by the prototypical IncL plasmid, whereas OXA-198 was carried by a peculiar IncHI-type plasmid. This carbapenemase gene was inserted within a class 1 integron located on a conjugative plasmid. This report describes the first occurrence of OXA-198 in <i>Enterobacterales</i>. ...[more]

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