Sodium Butyrate Protects N2a Cells against A? Toxicity In Vitro.
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ABSTRACT:
SUBMITTER: Sun J
PROVIDER: S-EPMC7180402 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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Sodium Butyrate Protects N2a Cells against A<i>β</i> Toxicity In Vitro.
Sun Jingxuan J Yuan Boyu B Wu Yancheng Y Gong Yuhong Y Guo Wenjin W Fu Shoupeng S Luan Yongxin Y Wang Wei W
Mediators of inflammation 20200415
Alzheimer's disease (AD) is a common neurodegenerative disease. A<i>β</i> plays an important role in the pathogenesis of AD. Sodium butyrate (NaB) is a short-chain fatty acid salt that exerts neuroprotective effects such as anti-inflammatory, antioxidant, antiapoptotic, and cognitive improvement in central nervous system diseases. The aim of this study is to research the protective effects of NaB on neurons against A<i>β</i> toxicity and to uncover the underlying mechanisms. The results showed t ...[more]
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