Dataset Information

Antibacterial and Antifungal Sesquiterpenoids from Aerial Parts of Anvillea garcinii.

ABSTRACT: Two new sesquiterpenoids belonging to the guaiane, 4?,9?,10?-trihydroxyguaia-11(13)en-12,6?-olide (1), and germacrane, 9?-hydroxyparthenolide-9-O-?-D-glucopyranoside (2), classes have been isolated from the leaves of the Saudi medicinal plant Anvillea garcinii along with seven known compounds (3-9). The structures of the new metabolites were elucidated by spectroscopic analysis, including one-dimensional (1D) and two-dimensional (2D) Nuclear Magnetic Resonance (NMR) and high-resolution electrospray ionization mass spectrometry (HR-ESIMS). The antimicrobial properties of 1-9 were screened against seven different pathogenic microbes, and compounds 1-3 showed a potent antifungal activity.

SUBMITTER: Perveen S

PROVIDER: S-EPMC7180898 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Antibacterial and Antifungal Sesquiterpenoids from Aerial Parts of Anvillea garcinii.

Perveen Shagufta S Alqahtani Jawaher J Orfali Raha R Aati Hanan Y HY Al-Taweel Areej M AM Ibrahim Taghreed A TA Khan Afsar A Yusufoglu Hasan S HS Abdel-Kader Maged S MS Taglialatela-Scafati Orazio O

Molecules (Basel, Switzerland) 20200409 7

Two new sesquiterpenoids belonging to the guaiane, 4α,9α,10α-trihydroxyguaia-11(13)en-12,6α-olide (1), and germacrane, 9β-hydroxyparthenolide-9-O-β-D-glucopyranoside (2), classes have been isolated from the leaves of the Saudi medicinal plant Anvillea garcinii along with seven known compounds (3-9). The structures of the new metabolites were elucidated by spectroscopic analysis, including one-dimensional (1D) and two-dimensional (2D) Nuclear Magnetic Res ...[more]

PMID: 32283756

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Dataset Information

Antibacterial and Antifungal Sesquiterpenoids from Aerial Parts of Anvillea garcinii.

Publications

Antibacterial and Antifungal Sesquiterpenoids from Aerial Parts of <i>Anvillea garcinii</i>.

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