Ontology highlight
ABSTRACT:
SUBMITTER: Vachhani P
PROVIDER: S-EPMC7181345 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Vachhani Pankit P Al Yacoub Raed R Miller Austin A Zhang Fan F Cronin Tara L TL Ontiveros Evelena P EP Thompson James E JE Griffiths Elizabeth A EA Wang Eunice S ES
Leukemia research 20181025
Acute myeloid leukemia (AML) in older patients is often associated with biologic and clinical characteristics that predict poor outcomes to cytarabine and anthracycline based induction chemotherapy (IC). The impact of hypomethylating agents (HMA) in the treatment of these high-risk patients is unknown. Here we retrospectively examined the remission rates and survival outcomes of 201 newly diagnosed patients ≥60 years old with therapy-related (t-AML), secondary (s-AML), or AML with myelodysplasia ...[more]