Dataset Information

Relationship between quality of life and behavioural disorders in children with persistent asthma: a Multiple Indicators Multiple Causes (MIMIC) model.

ABSTRACT: Knowledge on multiple interdependences between quality of life (QoL) and behavioural problems in relation to asthma severity and control is undetermined. The aims of the study were: (i) to assess the relationship of QoL and behavioural problems with asthma severity and control (ii) to predict children's "abnormal/borderline" status with variation in QoL. For these purposes a multicenter case-control study on 47 Severe Asthma (SA) and 94 Moderate Asthma (MA) children was performed. The MIMIC approach was applied to investigate the effect of SA and non-controlled asthma (NC) on QoL and behavioural disorders. Logistic regression was used to estimate probabilities of having an "abnormal/borderline" status with variation in QoL. The MIMIC model showed that the magnitude of the effect of SA and NC was larger on QoL (??=?-0.37 and ??=?-0.30, respectively) than on behavioural problems (??=?0.27). With regards to the probability of having a borderline status, in MA a QoL of 1 returned a probability of 0.81, whereas in SA a QoL of 1 returned a probability of 0.89. In conclusion, SA children are highly affected by impaired QoL and behavioural problems. The MIMIC model allowed us to obtain a comprehensive assessment of QoL and behavioural problems with asthma severity and control.

SUBMITTER: Montalbano L

PROVIDER: S-EPMC7181655 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Relationship between quality of life and behavioural disorders in children with persistent asthma: a Multiple Indicators Multiple Causes (MIMIC) model.

Montalbano Laura L Ferrante Giuliana G Montella Silvia S Cilluffo Giovanna G Di Marco Antonio A Bozzetto Sara S Di Palmo Emanuela E Licari Amelia A Leonardi Lucia L Caldarelli Valeria V Ghezzi Michele M La Grutta Stefania S Rusconi Franca F

Scientific reports 20200424 1

Knowledge on multiple interdependences between quality of life (QoL) and behavioural problems in relation to asthma severity and control is undetermined. The aims of the study were: (i) to assess the relationship of QoL and behavioural problems with asthma severity and control (ii) to predict children's "abnormal/borderline" status with variation in QoL. For these purposes a multicenter case-control study on 47 Severe Asthma (SA) and 94 Moderate Asthma (MA) children was performed. The MIMIC appr ...[more]

PMID: 32332757

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Project description:The analysis of response time has received increasing attention during the last decades, since evidence from several studies supported the argument that there is a direct relationship between item response time and test performance. The aim of this study was to investigate whether item response latency affects person's ability parameters, in that it represents an adaptive or maladaptive practice. To examine the above research question data from 8,475 individuals completing the computerized version of the Postgraduate General Aptitude Test (PAGAT) were analyzed. To determine the extent to which response latency affects person's ability, we used a Multiple Indicators Multiple Causes (MIMIC) model, in which every item in a scale was linked to its corresponding covariate (i.e., item response latency). We ran the MIMIC model within the Item Response Theory (IRT) framework (2-PL model). The results supported the hypothesis that item response latency could provide valuable information for getting more accurate estimations for persons' ability levels. Results indicated that for individuals who invest more time on easy items, their likelihood of success does not improve, most likely because slow and fast responders have significantly different levels of ability (fast responders are of higher ability compared to slow responders). Consequently, investing more time for low ability individuals does not prove to be adaptive. The opposite was found for difficult items: individuals spending more time on difficult items increase their likelihood of success, more likely because they are high achievers (in difficult items individuals who spent more time were of significantly higher ability compared to fast responders). Thus, it appears that there is an interaction between the difficulty of the item and person abilities that explain the effects of response time on likelihood of success. We concluded that accommodating item response latency in a computerized assessment model, can inform test quality and test takers' behavior, and in that way, enhance score measurement accuracy.

Dataset Information

Relationship between quality of life and behavioural disorders in children with persistent asthma: a Multiple Indicators Multiple Causes (MIMIC) model.

Publications

Relationship between quality of life and behavioural disorders in children with persistent asthma: a Multiple Indicators Multiple Causes (MIMIC) model.

Similar Datasets

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