Developmental variability channels mouse molar evolution.
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ABSTRACT:
SUBMITTER: Hayden L
PROVIDER: S-EPMC7182435 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Publications
Developmental variability channels mouse molar evolution.
Hayden Luke L Lochovska Katerina K Sémon Marie M Renaud Sabrina S Delignette-Muller Marie-Laure ML Vilcot Maurine M Peterkova Renata R Hovorakova Maria M Pantalacci Sophie S
eLife 20200212
Do developmental systems preferentially produce certain types of variation that orient phenotypic evolution along preferred directions? At different scales, from the intra-population to the interspecific, the murine first upper molar shows repeated anterior elongation. Using a novel quantitative approach to compare the development of two mouse strains with short or long molars, we identified temporal, spatial and functional differences in tooth signaling center activity, that arise from differen ...[more]
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