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Long-term work retention after treatment for cancer: a systematic review and meta-analysis.


ABSTRACT:

Purpose

Almost half of people diagnosed with cancer are working age. Survivors have increased risk of unemployment, but little is known about long-term work retention. This systematic review and meta-analysis assessed work retention and associated factors in long-term cancer survivors.

Methods

We searched Medline/Pubmed, Embase, PsychINFO, and CINAHL for studies published 01/01/2000-08/01/2019 reporting work retention in adult cancer survivors ??2 years post-diagnosis. Survivors had to be in paid work at diagnosis. Pooled prevalence of long-term work retention was estimated. Factors associated with work retention from multivariate analysis were synthesized.

Results

Twenty-nine articles, reporting 21 studies/datasets including 14,207 cancer survivors, were eligible. Work retention was assessed 2-14 years post-diagnosis. Fourteen studies were cross-sectional, five were prospective, and two contained both cross-sectional and prospective elements. No studies were scored as high quality. The pooled estimate of prevalence of long-term work retention in cancer survivors working at diagnosis was 0.73 (95%CI 0.69-0.77). The proportion working at 2-2.9 years was 0.72; at 3-3.9 years 0.80; at 4-4.9 years 0.75; at 5-5.9 years 0.74; and 6+?years 0.65. Pooled estimates did not differ by cancer site, geographical area, or study design. Seven studies assessed prognostic factors for work retention: older age, receiving chemotherapy, negative health outcomes, and lack of work adjustments were associated with not working.

Conclusion

Almost three-quarters of long-term cancer survivors working at diagnosis retain work.

Implications for cancer survivors

These findings are pertinent for guidelines on cancer survivorship care. Professionals could focus support on survivors most likely to have poor long-term work outcomes.

SUBMITTER: de Boer AG 

PROVIDER: S-EPMC7182621 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Long-term work retention after treatment for cancer: a systematic review and meta-analysis.

de Boer Angela Gem AG   Torp Steffen S   Popa Adela A   Horsboel Trine T   Zadnik Vesna V   Rottenberg Yakir Y   Bardi Edit E   Bultmann Ute U   Sharp Linda L  

Journal of cancer survivorship : research and practice 20200311 2


<h4>Purpose</h4>Almost half of people diagnosed with cancer are working age. Survivors have increased risk of unemployment, but little is known about long-term work retention. This systematic review and meta-analysis assessed work retention and associated factors in long-term cancer survivors.<h4>Methods</h4>We searched Medline/Pubmed, Embase, PsychINFO, and CINAHL for studies published 01/01/2000-08/01/2019 reporting work retention in adult cancer survivors ≥ 2 years post-diagnosis. Survivors h  ...[more]

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