Ontology highlight
ABSTRACT:
SUBMITTER: Su X
PROVIDER: S-EPMC7183339 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Su Xiangyu X Zhang Jing J Fu Chenchun C Xiao Mingzhe M Wang Cailian C
OncoTargets and therapy 20200421
<h4>Background</h4>Penile squamous cell carcinoma (PSCC) bears poor prognosis due to its rarity and limited treatment options, especially after failure of standard treatments. Effective therapeutic options were desperately needed.<h4>Case presentation</h4>We report a recurrent metastatic PSCC patient with positive programmed death ligand 1 (PD-L1) expression (≥10%) and tumor mutation burden (TMB) of 8.87 (Muts/Mb) who obtained significant response to immunotherapy, with progression-free survival ...[more]