Alterations of neural network organization during REM sleep in women: implication for sex differences in vulnerability to mood disorders.

ABSTRACT:

Background

Sleep plays an important role in vulnerability to mood disorders. However, despite the existence of sex differences in vulnerability to mood disorders, no study has yet investigated the sex effect on sleep network organization and its potential involvement in vulnerability to mood disorders. The aim of our study was to empirically investigate the sex effect on network organization during REM and slow-wave sleep using the effective connectivity measured by Granger causality.

Methods

Polysomnographic data from 44 healthy individuals (28 men and 16 women) recruited prospectively were analysed. To obtain the 19 × 19 connectivity matrix of all possible pairwise combinations of electrodes by Granger causality method from our EEG data, we used the Toolbox MVGC multivaria

SUBMITTER: Hein M 

PROVIDER: S-EPMC7183628 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature