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Age-Period-Cohort Analysis of HIV Mortality in China: Data from the Global Burden of Disease Study 2016.


ABSTRACT: The aim of this study was to investigate the long-term trends of human immunodeficiency virus (HIV) mortality in China and its associations with age, period and birth cohort. We used HIV mortality data obtained from the Global Burden of Disease Study (GBD) 2016 and analysed the data with an age-period-cohort framework. Age effects indicate different risks of different outcomes at specific periods in life; period effects reflect population- wide exposure at a circumscribed point in time; and cohort effects generally reflect differences in risk across birth cohorts.Our results showed that the overall annual percentage change (net drift) of HIV mortality was 11.3% (95% CI: 11.0% to 11.6%) for males and 7.2% (95% CI: 7.0% to 7.5%) for females, and the annual percentage changes in each age group (local drift) were greater than 5% (p?

SUBMITTER: Gao D 

PROVIDER: S-EPMC7184615 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Age-Period-Cohort Analysis of HIV Mortality in China: Data from the Global Burden of Disease Study 2016.

Gao Disi D   Zou Zhiyong Z   Zhang Wenjing W   Chen Tianqi T   Cui Wenxin W   Ma Yinghua Y  

Scientific reports 20200427 1


The aim of this study was to investigate the long-term trends of human immunodeficiency virus (HIV) mortality in China and its associations with age, period and birth cohort. We used HIV mortality data obtained from the Global Burden of Disease Study (GBD) 2016 and analysed the data with an age-period-cohort framework. Age effects indicate different risks of different outcomes at specific periods in life; period effects reflect population- wide exposure at a circumscribed point in time; and coho  ...[more]

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