Ontology highlight
ABSTRACT:
SUBMITTER: Tan HE
PROVIDER: S-EPMC7185044 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Tan Hwei-Ee HE Sisti Alexander C AC Jin Hao H Vignovich Martin M Villavicencio Miguel M Tsang Katherine S KS Goffer Yossef Y Zuker Charles S CS
Nature 20200415 7804
The taste of sugar is one of the most basic sensory percepts for humans and other animals. Animals can develop a strong preference for sugar even if they lack sweet taste receptors, indicating a mechanism independent of taste<sup>1-3</sup>. Here we examined the neural basis for sugar preference and demonstrate that a population of neurons in the vagal ganglia and brainstem are activated via the gut-brain axis to create preference for sugar. These neurons are stimulated in response to sugar but n ...[more]