Clinical and Biological Significances of a Methyltransferase-Related Signature in Diffuse Glioma.
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ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC7185060 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Clinical and Biological Significances of a Methyltransferase-Related Signature in Diffuse Glioma.
Zhang Ying Y Liu Yuqing Y Liu Hanjie H Zhao Zheng Z Wu Fan F Zeng Fan F
Frontiers in oncology 20200420
Methylation of DNA, RNA or protein is a reversible modification. The proteins and genes that regulate this modification can be a candidate target for tumor therapy. However, the characteristics of methyltransferase related genes in glioma remain obscure. In this study, we systematically analyzed the relationship between methyltransferase-related genes expression profiles and outcomes in glioma patients based on The Cancer Genome Atlas and Chinese Glioma Genome Atlas RNA sequencing datasets. Cons ...[more]
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