Causal Role of Motor Preparation during Error-Driven Learning.

ABSTRACT: Current theories suggest that an error-driven learning process updates trial-by-trial to facilitate motor adaptation. How this process interacts with motor cortical preparatory activity-which current models suggest plays a critical role in movement initiation-remains unknown. Here, we evaluated the role of motor preparation during visuomotor adaptation. We found that preparation time was inversely correlated to variance of errors on current trials and mean error on subsequent trials. We also found causal evidence that intracortical microstimulation during motor preparation was sufficient to disrupt learning. Surprisingly, stimulation did not affect current trials, but instead disrupted the update computation of a learning process, thereby affecting subsequent trials. This is consistent wit

SUBMITTER: Vyas S 

PROVIDER: S-EPMC7185427 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature