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Calculated initial parenteral treatment of bacterial infections: Pharmacokinetics and pharmacodynamics.

ABSTRACT: This is the third chapter of the guideline "Calculated initial parenteral treatment of bacterial infections in adults - update 2018" in the 2nd updated version. The German guideline by the Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. (PEG) has been translated to address an international audience. The chapter features the pharmacokinetic and pharmacodynamics properties of the most frequently used antiinfective agents.

SUBMITTER: Derendorf H

PROVIDER: S-EPMC7186811 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Calculated initial parenteral treatment of bacterial infections: Pharmacokinetics and pharmacodynamics.

Derendorf Hartmut H Heinrichs Tobias T Reimers Tobias T Lebert Cordula C Brinkmann Alexander A

GMS infectious diseases 20200326

This is the third chapter of the guideline "Calculated initial parenteral treatment of bacterial infections in adults - update 2018" in the 2<sup>nd</sup> updated version. The German guideline by the Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. (PEG) has been translated to address an international audience. The chapter features the pharmacokinetic and pharmacodynamics properties of the most frequently used antiinfective agents. ...[more]

PMID: 32373442

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Calculated initial parenteral treatment of bacterial infections: Bacterial gastrointestinal infections.

Project description:This is the fourteenth chapter of the guideline "Calculated initial parenteral treatment of bacterial infections in adults - update 2018" in the 2nd updated version. The German guideline by the Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. (PEG) has been translated to address an international audience. Bacterial gastrointestinal infections are still the leading cause of death worldwide. The chapter describes the etiology of bacterial gastrointestinal infections in Germany and their frequency. Recommendations are given for the calculated therapy of these infections and for targeted antibiotic therapy for known pathogens. Particular attention is paid to Clostridium difficile. The diagnostic and therapeutic options of antibiotic therapy of the various infection patterns in this pathogen are discussed.

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