Motor Cortex Reorganization in Limb Amputation: A Systematic Review of TMS Motor Mapping Studies.

ABSTRACT: Purpose: The purpose of this systematic review is to evaluate motor cortex reorganization in amputees as indexed by transcranial magnetic stimulation (TMS) cortical mapping and its relationship with phantom limb pain (PLP). Methods: Pubmed database were systematically searched. Three independent researchers screened the relevant articles, and the data of motor output maps, including the number of effective stimulation sites, center of gravity (CoG) shift, and their clinical correlations were extracted. We calculated a pooled CoG shift for motor cortex TMS mapping. Results: The search yielded 468 articles, 11 were included. Three studies performed correlation between the cortical changes and PLP intensity, and only one study compared cortical mapping changes between amputees with pain and w

SUBMITTER: Gunduz ME 

PROVIDER: S-EPMC7187753 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature