Ontology highlight
ABSTRACT:
SUBMITTER: Jeha GM
PROVIDER: S-EPMC7188377 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Jeha George M GM Wesley Tiffany T Cataldo Vince D VD
Journal of hematology 20200423 1-2
Identification of chromosomal abnormalities in patients with acute myeloid leukemia (AML) has contributed substantially to our current understanding of the molecular pathogenesis underlying leukemogenesis, and risk-stratification based on molecular abnormalities both influences treatment strategies and aids in determining prognosis. While over 300 established mutations have been documented in AML, the enhanced availability of genetic analysis and the increase in awareness of uncommon chromosomal ...[more]