Ontology highlight
ABSTRACT:
SUBMITTER: Elmezayen AD
PROVIDER: S-EPMC7189413 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Elmezayen Ammar D AD Al-Obaidi Anas A Şahin Alp Tegin AT Yelekçi Kemal K
Journal of biomolecular structure & dynamics 20200426 8
In December 2019, COVID-19 epidemic was described in Wuhan, China, and the infection has spread widely affecting hundreds of thousands. Herein, an effort was made to identify commercially available drugs in order to repurpose them against coronavirus by the means of structure-based virtual screening. In addition, ZINC15 library was used to identify novel leads against main proteases. Human TMPRSS2 3D structure was first generated using homology modeling approach. Our molecular docking study show ...[more]