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CCMetagen: comprehensive and accurate identification of eukaryotes and prokaryotes in metagenomic data.


ABSTRACT: There is an increasing demand for accurate and fast metagenome classifiers that can not only identify bacteria, but all members of a microbial community. We used a recently developed concept in read mapping to develop a highly accurate metagenomic classification pipeline named CCMetagen. The pipeline substantially outperforms other commonly used software in identifying bacteria and fungi and can efficiently use the entire NCBI nucleotide collection as a reference to detect species with incomplete genome data from all biological kingdoms. CCMetagen is user-friendly, and the results can be easily integrated into microbial community analysis software for streamlined and automated microbiome studies.

SUBMITTER: Marcelino VR 

PROVIDER: S-EPMC7189439 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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CCMetagen: comprehensive and accurate identification of eukaryotes and prokaryotes in metagenomic data.

Marcelino Vanessa R VR   Clausen Philip T L C PTLC   Buchmann Jan P JP   Wille Michelle M   Iredell Jonathan R JR   Meyer Wieland W   Lund Ole O   Sorrell Tania C TC   Holmes Edward C EC  

Genome biology 20200428 1


There is an increasing demand for accurate and fast metagenome classifiers that can not only identify bacteria, but all members of a microbial community. We used a recently developed concept in read mapping to develop a highly accurate metagenomic classification pipeline named CCMetagen. The pipeline substantially outperforms other commonly used software in identifying bacteria and fungi and can efficiently use the entire NCBI nucleotide collection as a reference to detect species with incomplet  ...[more]

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