Different profiles of body mass index variation among patients with multidrug-resistant tuberculosis: a retrospective cohort study.

ABSTRACT: BACKGROUND:Despite the predictive role of body weight variation in treatment outcome in multidrug-resistant tuberculosis (MDR-TB), few corroborating data are available. We studied weight variation in patients with MDR-TB to identify groups of weight change and to determine factors that influence these changes. METHODS:We analyzed patients with rifampicin resistance who were treated with an MDR-TB treatment regimen between June 07, 2016 and June 22, 2018 at three major drug-resistant TB centers in Guinea. Patients were seen monthly until the end of treatment. Clinical outcome was the body mass index (BMI). We used a linear mixed model to analyze trajectories of BMI and a latent class mixed model to identify groups of BMI trajectories. RESULTS:Of 232 patients treated for MDR-TB during the st

SUBMITTER: Diallo A 

PROVIDER: S-EPMC7189596 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature