Ontology highlight
ABSTRACT:
SUBMITTER: Zeng W
PROVIDER: S-EPMC7190499 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Zeng Weihong W Liu Guangfeng G Ma Huan H Zhao Dan D Yang Yunru Y Liu Muziying M Mohammed Ahmed A Zhao Changcheng C Yang Yun Y Xie Jiajia J Ding Chengchao C Ma Xiaoling X Weng Jianping J Gao Yong Y He Hongliang H Jin Tengchuan T
Biochemical and biophysical research communications 20200430 3
The nucleocapsid (N) protein is an important antigen for coronavirus, which participate in RNA package and virus particle release. In this study, we expressed the N protein of SARS-CoV-2 and characterized its biochemical properties. Static light scattering, size exclusive chromatography, and small-angle X-ray scattering (SAXS) showed that the purified N protein is largely a dimer in solution. CD spectra showed that it has a high percentage of disordered region at room temperature while it was be ...[more]