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Ability of the post-operative ALBI grade to predict the outcomes of hepatocellular carcinoma after curative surgery.


ABSTRACT: The albumin-bilirubin (ALBI) grade has been validated as a significant predictor for hepatocellular carcinoma (HCC). However, there is little information about the impact of postoperative ALBI grade in patients with HCC who are undergoing liver resection. We enrolled 525 HCC patients who received primary resection from April 2001 to March 2017. The impact of the pre- and post-operative ALBI grades on overall survival (OS) and recurrence-free survival (RFS) were analyzed by multivariate analysis. During the follow-up period (mean, 65 months), 253 (48.1%) patients experienced recurrence, and 85 (16.2%) patients died. Multivariate analysis revealed that diabetes mellitus (DM) (p?=?0.011), alpha-fetoprotein levels (AFP) (p?

SUBMITTER: Cho WR 

PROVIDER: S-EPMC7190718 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Ability of the post-operative ALBI grade to predict the outcomes of hepatocellular carcinoma after curative surgery.

Cho Wei-Ru WR   Hung Chao-Hung CH   Chen Chien-Hung CH   Lin Chih-Che CC   Wang Chih-Chi CC   Liu Yueh-Wei YW   Wu Yi-Ju YJ   Yong Chee-Chien CC   Chen Kuang-Den KD   Tsai Yu-Chieh YC   Hu Tsung-Hui TH   Tsai Ming-Chao MC  

Scientific reports 20200429 1


The albumin-bilirubin (ALBI) grade has been validated as a significant predictor for hepatocellular carcinoma (HCC). However, there is little information about the impact of postoperative ALBI grade in patients with HCC who are undergoing liver resection. We enrolled 525 HCC patients who received primary resection from April 2001 to March 2017. The impact of the pre- and post-operative ALBI grades on overall survival (OS) and recurrence-free survival (RFS) were analyzed by multivariate analysis.  ...[more]

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