Identification of key lncRNAs as prognostic prediction models for colorectal cancer based on LASSO.
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ABSTRACT:
SUBMITTER: Huang X
PROVIDER: S-EPMC7191144 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Identification of key lncRNAs as prognostic prediction models for colorectal cancer based on LASSO.
Huang Xiao X Cai Wei W Yuan Wenliang W Peng Sihua S
International journal of clinical and experimental pathology 20200401 4
Colorectal cancer (CRC) is one of the most common malignancies, with varying prognoses and a high mortality. There is an urgent need to establish a new prediction model to predict the survival risk of CRC patients. The long non-coding RNAs (lncRNAs) expression profiles and corresponding clinical information of CRC patients were obtained from The Cancer Genome Atlas, TCGA. We identified a total of 1,176 lncRNAs differentially expressed between 480 CRC and 41 normal tissues. In the training test, ...[more]
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