Mindfulness-based crisis interventions (MBCI) for psychosis within acute inpatient psychiatric settings; a feasibility randomised controlled trial.
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ABSTRACT: BACKGROUND:Inpatient psychiatric care is a scarce and expensive resource in the National Health Service (NHS), with chronic bed shortages being partly driven by high re-admission rates. Brief inpatient talking therapies for psychosis could help reduce re-admission rates. The primary aim was to assess feasibility and acceptability of a novel, brief, mindfulness-based intervention for inpatients with psychosis. The secondary aim was to collect pilot outcome data on readmission rate, at 6 and 12?months (m) post discharge, and self-report symptom measures at 6?m. METHODS:The amBITION study (BrIef Talking therapIes ON wards) was a parallel group, feasibility randomised controlled trial (RCT). In addition to treatment as usual (TAU), eligible inpatients with psychotic symptoms were randomly allocated to receive either (Mindfulness-Based Crisis Intervention; MBCI) or a control intervention (Social Activity Therapy; SAT), for 1-5 sessions. RESULTS:Fifty participants were recruited (26 MBCI; 24 SAT); all received at least 1 therapy session (mean?=?3). Follow-up rates were 98% at 6?m and 96% at 12?m for service use data extracted from clinical notes, and 86% for self-report measures. At 6?m follow-up, re-admission rates were similar across groups (MBCI?=?6, SAT?=?5; odds ratio?=?1.20, 95% CI: 0.312-4.61). At 12?m follow-up, re-admissions were lower in the MBCI group (MBCI?=?7, SAT?=?11; odds ratio?=?0.46, 95% CI: 0.14-1.51). Three participants experienced adverse events; none was related to trial participation. CONCLUSIONS:Delivering a brief mindfulness-based inpatient intervention for psychosis is feasible and acceptable, and may reduce risk of short-term readmission. These promising findings warrant progression to a larger clinical effectiveness trial. TRIAL REGISTRATION:ISRCTN37625384.
SUBMITTER: Jacobsen P
PROVIDER: S-EPMC7191699 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
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