An implantable multifunctional neural microprobe for simultaneous multi-analyte sensing and chemical delivery.
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ABSTRACT:
SUBMITTER: Wang B
PROVIDER: S-EPMC7192313 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Publications
An implantable multifunctional neural microprobe for simultaneous multi-analyte sensing and chemical delivery.
Wang Bo B Wen Ximiao X Cao Yan Y Huang Shan S Lam Hoa A HA Liu Tingyi Leo TL Chung Pei-Shan PS Monbouquette Harold G HG Chiou Pei-Yu PY Maidment Nigel T NT
Lab on a chip 20200325 8
A multifunctional chemical neural probe fabrication process exploiting PDMS thin-film transfer to incorporate a microfluidic channel onto a silicon-based microelectrode array (MEA) platform, and enzyme microstamping to provide multi-analyte detection is described. The Si/PDMS hybrid chemtrode, modified with a nano-based on-probe IrOx reference electrode, was validated in brain phantoms and in rat brain. ...[more]
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