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After the COVID-19 Pandemic: Returning to Normalcy or Returning to a New Normal?

ABSTRACT: The novel coronavirus, severe acute respiratory coronavirus 2 (SARS-CoV-2), pandemic has delivered a profound and negative impact on the United States. The suspension of elective surgeries including arthroplasty will have a lasting effect on all stakeholders including patients, physicians, and healthcare organizations within the US healthcare system. Resumption of elective hip and knee arthroplasty will need to be carefully focused. The purpose of this work is to address potential strategies, concerns, and regulatory barriers in restarting elective hip and knee arthroplasty in the United States.

SUBMITTER: Zeegen EN 

PROVIDER: S-EPMC7195118 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Evidence for activation of endogenous opioid systems in mice following short exposure to stable flies.

Colwell D D DD   Kavaliers M M  

Medical and veterinary entomology 19920401 2

Biting flies influence both physiology and behaviour of domestic and wild animals. This study demonstrates that brief (30 min) exposure of male and female mice to stable flies leads to significant increases in nociceptive responses, indicative of the induction of analgesia. The biting fly-induced analgesia was mediated by endogenous opioid systems as it was blocked by the prototypic opiate antagonist naloxone. Exposure for 30 min to the bedding of biting fly-exposed mice also induced significant  ...[more]