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ABSTRACT: Background
Studies have found that pairing vagus nerve stimulation (VNS) with motor activity accelerates cortical reorganization. This synchronous pairing may enhance motor recovery.Objective
To develop and validate a motor-activated auricular vagus nerve stimulation (MAAVNS) system as a potential neurorehabilitation tool.Methods
We created MAAVNS and validated its function as part of an ongoing clinical trial investigating whether taVNS-paired rehabilitation enhances oromotor learning. We compared 3 different MAAVNS EMG electrode configurations in 3 neonates. The active lead was placed over the buccinator muscle. Reference lead placements were orbital, temporal or frontal.Results
The frontal reference lead produced the highest sensitivity (0.87 ± 0.07 (n =
SUBMITTER: Cook DN
PROVIDER: S-EPMC7196027 | biostudies-literature | 2020 May - Jun
REPOSITORIES: biostudies-literature