Ontology highlight
ABSTRACT:
SUBMITTER: Sylos-Labini F
PROVIDER: S-EPMC7196819 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Sylos-Labini Francesca F La Scaleia Valentina V Cappellini Germana G Fabiano Adele A Picone Simonetta S Keshishian Elena S ES Zhvansky Dmitry S DS Paolillo Piermichele P Solopova Irina A IA d'Avella Andrea A Ivanenko Yury Y Lacquaniti Francesco F
Proceedings of the National Academy of Sciences of the United States of America 20200413 17
Mature locomotion involves modular spinal drives generating a set of fundamental patterns of motoneuron activation, each timed at a specific phase of locomotor cycles and associated with a stable muscle synergy. How locomotor modules develop and to what extent they depend on prior experience or intrinsic programs remains unclear. To address these issues, we herein leverage the presence at birth of two types of locomotor-like movements, spontaneous kicking and weight-bearing stepping. The former ...[more]