Modulation of value-based decision making behavior by subregions of the rat prefrontal cortex.

ABSTRACT: RATIONALE:During value-based decision-making, organisms make choices on the basis of reward expectations, which have been formed during prior action-outcome learning. Although it is known that neuronal manipulations of different subregions of the rat prefrontal cortex (PFC) have qualitatively different effects on behavioral tasks involving value-based decision-making, it is unclear how these regions contribute to the underlying component processes. OBJECTIVES:Assessing how different regions of the rodent PFC contribute to component processes of value-based decision-making behavior, including reward (or positive feedback) learning, punishment (or negative feedback) learning, response persistence, and exploration versus exploitation. METHODS:We performed behavioral modeling of data of rats i

SUBMITTER: Verharen JPH 

PROVIDER: S-EPMC7196947 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature