Identification of B-cell epitopes on the betanodavirus capsid protein.
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ABSTRACT:
SUBMITTER: Costa JZ
PROVIDER: S-EPMC7197462 | biostudies-literature | 2007 Jul
REPOSITORIES: biostudies-literature
Publications
Identification of B-cell epitopes on the betanodavirus capsid protein.
Costa J Z JZ Adams A A Bron J E JE Thompson K D KD Starkey W G WG Richards R H RH
Journal of fish diseases 20070701 7
The pepscan procedure was used to identify betanodavirus B-cell epitopes recognized by neutralizing mouse monoclonal antibodies (MAbs) and serum samples obtained from sea bass, Dicentrarchus labrax, naturally infected with betanodavirus. Pepscan was performed with a panel of thirty-four 12-mer synthetic peptides that mimicked the entire betanodavirus capsid protein. Sea bass serum samples reacted strongly with three regions of the capsid protein comprising amino acid residues 1-32, 91-162 and 18 ...[more]
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