Leaflet thickening and stent geometry in sutureless bioprosthetic aortic valves.

ABSTRACT: Underexpansion of transcatheter heart valves and the surgically implanted Perceval sutureless aortic valve bioprosthesis has been suggested as an underlying mechanism for hypo-attenuated leaflet thickening (HALT). This was a single-center prospective observational study that included 47 patients who underwent surgical aortic valve replacement with the Perceval sutureless bioprosthesis (LivaNova, London, United Kingdom) from 2012 to 2016 and were studied by four-dimensional cardiac computed tomography (CT). The association between overall and regional expansion and the prevalence of HALT was analyzed. In total 46 patients were included in the analysis. HALT was found in 39.1% of patients and the mean overall prosthesis expansion was 75.5?±?5.2% (range 64.6-84.8%). Overall expansion did not differ between patients with HALT compared with patients without HALT (mean overall expansion 74.0?±?5.2% vs. 76.5?±?5.0%, P?=?0.11). The prevalence of HALT was lower in patients with overall expansion?>?80% compared to patients with expansion?

SUBMITTER: Themudo R 

PROVIDER: S-EPMC7198640 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature