MicroRNA Expression in Women With and Without Polycystic Ovarian Syndrome Matched for Body Mass Index.

ABSTRACT: Background: Despite several authors who have hypothesized that alterations of small noncoding RNAs (miR) are implicated in the etiopathogenesis of polycystic ovarian syndrome (PCOS), contrasting findings have been reported so far. Discrepancies in body mass index (BMI) levels may account for these differences; therefore, the aim of the present study was to determine whether miR differed in serum samples collected from age- and BMI-matched control and PCOS women. Methods: In a cross-sectional study, miR were measured using quantitative polymerase chain reaction in 29 women with anovulatory PCOS women and 29 control women who were in the follicular phase of their menstrual cycle, from the local biobank. Results: One hundred seventy-six miR were detected, of which 15 miR

SUBMITTER: Butler AE 

PROVIDER: S-EPMC7199502 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature